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Locus coeruleus rostro-caudal functional connectivity gradient

Biomarker

1 paper2 findings

  • Humans1

Effects

2

Emotion regulation performance

downin humans1

1 study

  1. Locus coeruleus rostro-caudal functional connectivity gradient impairs emotion regulation performance in humans.

    “A more 'old-like' LC rostro-caudal functional connectivity gradient, but not LC signal intensity, was related to lower HRV and worse reappraisal outcomes.”

    Humans

    Different association patterns of emotion regulation and heart rate variability in older and younger adults

    Brain communications10 Oct 2025

Heart rate variability

downin humans1

1 study

  1. Locus coeruleus rostro-caudal functional connectivity gradient decreases heart rate variability in humans.

    “A more 'old-like' LC rostro-caudal functional connectivity gradient, but not LC signal intensity, was related to lower HRV and worse reappraisal outcomes.”

    Humans

    Different association patterns of emotion regulation and heart rate variability in older and younger adults

    Brain communications10 Oct 2025

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