Left atrial ejection fraction

1. Left atrial ejection fraction improves incident heart failure discrimination in humans.

   “Incorporating LAEF into the ARIC HF risk model significantly improved discrimination for incident HF at both 3 and 5 years.”

   Humanswithout prevalent HFn = 30,052

   Associations of Atrial Cardiomyopathy Markers with Incident Heart Failure

   Research Square·15 Aug 2026Preprint

1. Left atrial ejection fraction raises the risk of heart failure in humans.

   “HF risk increasing at lower LAEF values. An LAEF threshold of approximately 50% identified participants at elevated HF risk.”

   Humanswithout prevalent HFn = 30,052

   Associations of Atrial Cardiomyopathy Markers with Incident Heart Failure

   Research Square·15 Aug 2026Preprint

2. Left atrial ejection fraction is associated with heart failure in humans.

   “Left atrial markers, including left atrial maximum volume index (LAViMax), left atrial minimum volume index (LAViMin), and left atrial ejection fraction (LAEF), were independently associated with incident HF.”

   Humanswithout prevalent HFn = 30,052

   Associations of Atrial Cardiomyopathy Markers with Incident Heart Failure

   Research Square·15 Aug 2026Preprint

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