KDM-BA.Accel

1. Benzene is associated with KDM-BA.Accel in humans.

   “BKMR suggested a positive overall association of the BTX mixture with KDM-BA.Accel, with SPMA and TTMA contributing most prominently.”

   HumansBKMR mixture analysis

   Exposure to benzene, toluene and xylenes (BTX) and biological aging: epidemiological evidence from Chinese industrial workers and mechanistic insights

   Environment international·5 Feb 2026

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1. Trans, trans-muconic acid is associated with KDM-BA.Accel in humans (β = 0.08, 95% CI: 0.01 to 0.14).

   “TTMA (β = 0.08, 95% CI: 0.01 to 0.14) were associated with higher KDM-BA.Accel”

   Humansfully adjusted modelsurine

   Exposure to benzene, toluene and xylenes (BTX) and biological aging: epidemiological evidence from Chinese industrial workers and mechanistic insights

   Environment international·5 Feb 2026

More on Trans, trans-muconic acid

1. S-phenylmercapturic acid is associated with KDM-BA.Accel in humans (β = 0.15, 95% CI: 0.07 to 0.24).

   “higher SPMA (β = 0.15, 95% CI: 0.07 to 0.24) and TTMA (β = 0.08, 95% CI: 0.01 to 0.14) were associated with higher KDM-BA.Accel”

   Humansfully adjusted modelsurine

   Exposure to benzene, toluene and xylenes (BTX) and biological aging: epidemiological evidence from Chinese industrial workers and mechanistic insights

   Environment international·5 Feb 2026

More on S-phenylmercapturic acid