Juxtacortical white matter hyperintensity volume

1. Cortisol is associated with juxtacortical white matter hyperintensity volume in humans (β = 0.03, 95% CI 0.00 to 0.06, adj. p = 0.31).

   “positively associated with juxtacortical WMH volume in individuals below 60 years (β(95%CI)=0.03(0.00,0.06), p = 0.03, adj. p = 0.31), though these associations were not significant after false discovery rate correction”

   Humansindividuals below 60 yearsn = 123

   Cross‐Sectional Links between Baseline Serum Cortisol Levels and Cognitive Performance, Sleep, and Brain MRI Findings in a Rural Aging South‐Indian Cohort

   AAIC 2025 abstract·23 Dec 2025

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