IgG1 response

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ST8SIA6

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ST8SIA6 decreases IgG1 response in mice.
“Additionally, an increased IgG1 response was observed upon T cell-dependent immunization.”
AnimalsShown by St8sia6 knockout following T cell-dependent immunization
Loss of ST8Sia6 mediated α-2,8-linked di-sialylation enhances T cell-dependent antibody responses and promotes autoimmunity in aged mice
Frontiers in immunologyJul 2, 2026

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Loss of ST8Sia6 mediated α-2,8-linked di-sialylation enhances T cell-dependent antibody responses and promotes autoimmunity in aged mice

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