Heartbeat-evoked response amplitude

Age decreases heartbeat-evoked response amplitude in humans.

“cortical heartbeat-evoked responses (HERs) showed distinct amplitude changes in the 180-320 ms window post the heartbeat including a systematic reduction in amplitude with age”

Humansn = 620

When the inner clock fades: Interoceptive decline and consolidation of phase resetting in cortical rhythms by cardiac events underlie healthy lifespan aging

Imaging neuroscience (Cambridge, Mass.)·29 Jul 2026