H2B monoubiquitination

Hippocampus is associated with H2B monoubiquitination in rats.

“monoubiquitination of histone H2B (H2Bubi), an epigenetic mechanism recently reported to be major regulator of the epigenome and transcriptome during memory formation in the young adult brain, decreases with age in the hippocampus of male rats”

Animalshippocampusmales

Increasing H2B Monoubiquitination Improves the Transcriptome and Memory in the Aged Hippocampus

eNeuro·Apr 8, 2025