Nature Communications
Neuron loss may weaken the brain’s spatial maps in aging mice
Silencing a neuron subgroup in young mice impaired how brain cells responded to location; older mice had fewer cells in this subgroup.Silencing a neuron subgroup in young mice impaired how brain cells responded to location; older mice had fewer cells in this subgroup.
Mouse studyMechanisms
Who was studiedYoung and old mice
What changedSilencing Bglap3+ neurons in young mice worsened how precisely brain cells responded to location
The catchAge-related neuron loss was observed; the intervention only silenced neurons in young mice