Frequency-adjusted symptom burden score

1. 2-DE protein spot #285 is associated with frequency-adjusted symptom burden score in humans.

   “The median overall symptom burden score was 45.0 (interquartile range, 6.5- 58.5) and was inversely correlated with spots #285 and #636.”

   Humansserumfemalesn = 27

   Proteomic biomarker candidates inversely associated with menopausal symptoms in midlife women

   medRxiv·22 Aug 2026Preprint

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