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Fecal immunochemical test positivity

There is 1 paper on fecal immunochemical test positivity in aging research: 1 observational study in people. The newest story, Oct 31, 2026: “Positive stool tests linked to colon and rectal cancer risk”.

Biomarker

1 paper studies it4 findings

1 new paper in 30 daysSee all 1

“double-positive FIT was associated with a markedly elevated risk of CRC incidence (HR=8.49, 95% CI: 7.67-9.39)”
Associations of fecal immunochemical test positivity with risks of cancer incidence and mortality: findings from a community-based screening program in Pudong New Area of Shanghai, ChinaFrontiers in oncology2026doi:10.3389/fonc.2026.1995452
  • Humans1

Associations

4

Upper gastrointestinal cancer mortality

upin humans1HR 1.37

1 study

  1. Fecal immunochemical test positivity is associated with upper gastrointestinal cancer mortality in humans (Single-positive FIT versus negative FIT) (HR 1.37, 95% CI 1.14-1.63).

    “upper gastrointestinal cancer incidence (double-positive HR=1.56, 95% CI: 1.27-1.93) and mortality (single-positive HR=1.37, 95% CI: 1.14-1.63)”

    HumansSingle-positive FIT versus negative FITMean follow-up of 6.7 yearsn = 427,560

    Positive stool tests linked to colon and rectal cancer risk

    Frontiers in oncology

Upper gastrointestinal cancer incidence

upin humans1HR 1.56

1 study

  1. Fecal immunochemical test positivity is associated with upper gastrointestinal cancer incidence in humans (Double-positive FIT versus negative FIT) (HR 1.56, 95% CI 1.27-1.93).

    “FIT positivity was also associated with increased risk of upper gastrointestinal cancer incidence (double-positive HR=1.56, 95% CI: 1.27-1.93)”

    HumansDouble-positive FIT versus negative FITMean follow-up of 6.7 yearsn = 427,560

    Positive stool tests linked to colon and rectal cancer risk

    Frontiers in oncology

More on Upper gastrointestinal cancer incidence

Colorectal cancer mortality

upin humans1HR 8.27

1 study

  1. Fecal immunochemical test positivity is associated with colorectal cancer mortality in humans (Double-positive FIT versus negative FIT) (HR 8.27, 95% CI 6.59-10.38).

    “double-positive FIT was associated with a markedly elevated risk of CRC incidence (HR=8.49, 95% CI: 7.67-9.39) and mortality (HR=8.27, 95% CI: 6.59-10.38)”

    HumansDouble-positive FIT versus negative FITMean follow-up of 6.7 yearsn = 427,560

    Positive stool tests linked to colon and rectal cancer risk

    Frontiers in oncology

Colorectal cancer incidence

upin humans1HR 8.49

1 study

  1. Fecal immunochemical test positivity is associated with colorectal cancer incidence in humans (Double-positive FIT versus negative FIT) (HR 8.49, 95% CI 7.67-9.39).

    “double-positive FIT was associated with a markedly elevated risk of CRC incidence (HR=8.49, 95% CI: 7.67-9.39)”

    HumansDouble-positive FIT versus negative FITMean follow-up of 6.7 yearsn = 427,560

    Positive stool tests linked to colon and rectal cancer risk

    Frontiers in oncology

More on Colorectal cancer incidence

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Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 01 paper in 12 months
Frontiers in Oncology

Positive stool tests linked to colon and rectal cancer risk

Two positive tests were linked to higher colon and rectal cancer rates than negative tests, with a hazard ratio—a measure of relative rates—of 8.49.Two positive tests were linked to higher colon and rectal cancer rates than negative tests, with a hazard ratio—a measure of relative rates—of 8.49.

Accepted, not yet published: cohort · 427,560 peopleCancer
Paper

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