International Journal of Biological Sciences
Modified compound reduced acute kidney injury in mice
Experiments in young male mice found that linking nicotinamide mononucleotide to a polymer improved kidney uptake and reduced injury over 48 hours.Experiments in young male mice found that linking nicotinamide mononucleotide to a polymer improved kidney uptake and reduced injury over 48 hours.
Mouse studyAcute kidney injury
Who was studiedMale mice with ischemia-induced acute kidney injury, 48 hours
What changedNMN-PEG reduced kidney tubule damage compared with untreated mice with acute kidney injury
The catchInjury outcomes ended at 48 hours after ischemia, leaving longer-term kidney recovery unmeasured