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Drusen volume

Biomarker

5 papers study it6 more mention it2 findings

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  • Humans4
  • Animals1

Associations

1

Age-related macular degeneration

upin humans2OR 2.59

2 studies

  1. Drusen volume raises the risk of age-related macular degeneration in humans (OR: 2.59, p = 0.049).

    “The multivariate regression model identified that drusen volume in the 3 mm ring (OR: 2.59, p = 0.049) and presence of IHRF (OR: 57.06, p < 0.001) remained as independent and significant risk factors for progression to late AMD.”

    Humansretina2 yearsn = 666

    Risk Factors for Progression of Age-Related Macular Degeneration: Population-Based Amish Eye Study

    Journal of clinical medicine

  2. Drusen volume is associated with age-related macular degeneration in humans (two-fold higher prevalence rate, p<0.001).

    “eyes where RPE-BrC volumes were >0 mm3 at baseline, this was associated with two-fold higher prevalence rate of any AMD at baseline (p<0.001)”

    Humans6 years

    Six-year incidence of age-related macular degeneration and correlation to OCT-derived drusen volume measurements in a Chinese population

    The British journal of ophthalmology

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