What does the research say about DNER?

DNER

There are 3 papers on DNER in aging research: 1 trial and 2 observational studies in people. The newest story, Nov 13, 2026: “Blood protein analysis points to possible fat-loss drug targets”.

Biomarker

3 papers study it1 finding

1 new paper in 30 daysSee all 3 papers on DNER

“DNER (OR = 0.7210, 95%CI 0.5265–0.9875, P = 0.0415), IL-15Rα (OR = 0.8035, 95%CI 0.6582–0.9809, P = 0.0316), and IL-18R1 (OR = 0.8090, 95%CI 0.6710–0.9753, P = 0.0262) levels were negatively associated with risk”

Bidirectional Mendelian randomization identifies differential causal associations between inflammatory cytokines and lung cancer subtypesDiscover oncology2026doi:10.1007/s12672-026-04615-y

Human trial1
Humans2

Associations

Small cell lung cancer

downin humans1OR 0.721

1 study

DNER is linked with a lower risk of small cell lung cancer in humans (OR = 0.7210, 95%CI 0.5265–0.9875).
“DNER (OR = 0.7210, 95%CI 0.5265–0.9875, P = 0.0415), IL-15Rα (OR = 0.8035, 95%CI 0.6582–0.9809, P = 0.0316), and IL-18R1 (OR = 0.8090, 95%CI 0.6710–0.9753, P = 0.0262) levels were negatively associated with risk”
Humans
Bidirectional Mendelian randomization identifies differential causal associations between inflammatory cytokines and lung cancer subtypes
Discover oncologyFeb 10, 2026

Latest

3 papers in 12 months

Communications MedicineNov 13

Blood protein analysis points to possible fat-loss drug targets

Genetically predicted levels of 21 proteins were linked to fat mass; seven had no clear link to the body's nonfat components.Genetically predicted levels of 21 proteins were linked to fat mass; seven had no clear link to the body's nonfat components.

Mendelian randomization · 368,000 peopleMechanisms