DNA methylation at aging-associated CpG sites

Chronological age is associated with DNA methylation at aging-associated CpG sites in humans (1202 aging-associated CpG sites; FDR < 5%).

“we identified 1202 aging-associated CpG sites (a-CpGs, FDR < 5%), in whole blood in a population with an especially narrow age range (40 - 49 years).”

Humansadjusted for cell type heterogeneitywhole blood

Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

BMC genomics·Feb 9, 2016