Disease-associated metabolomic trait discoveries
Biomarker1 paper1 finding
- Humans1
Upstream
1MCPS-trained models
upin humans1
1 study
MCPS-trained models
upin humans1
MCPS-trained models increase disease-associated metabolomic trait discoveries in humans (5-fold).
“using MCPS-trained (vs. INTERVAL-trained) models to predict metabolomic traits yielded five times as many significant associations (FDR-corrected P<0.05)”
Humansin AMR participants of All of Us cohort across ischaemic heart disease, type 2 diabetes, and chronic kidney disease
Enhanced power and transferability for genetics-driven metabolomic biomarker discovery in admixed American cohorts · medRxiv · 7 Sep 2026 · Preprint