bioRxiv
Age-linked RNA shifts in mice mostly point to gene regulation
Across mouse tissues, 36.5–42.6% of switches altered the predicted protein-coding sequence, while 11–18% involved RNA versions encoding an identical protein.Across mouse tissues, 36.5–42.6% of switches altered the predicted protein-coding sequence, while 11–18% involved RNA versions encoding an identical protein.
Preprint: mouse studyAI & data
Who was studiedNaturally aging mice and Ercc1 knockout mice
What changedAcross mouse tissues, 36.5-42.6% of age-linked RNA switches altered the predicted protein-coding sequence
The catchRNA features and computer predictions do not directly measure effects on tissue function