Delta age

Biomarker2 papers3 findings

  • Humans2

Interventions

1

GLP-1 receptor agonists

downin humans1−79%Low certainty

1 study
  1. GLP-1 receptor agonists decrease delta age in humans (78.6%).

    Humanscardiometabolic drug therapyn = 1,178

    Cardiometabolic Therapy Reduces Electrocardiogram-Derived Biological Age: A Time-Weighted Analysis · AHA Scientific Sessions 2025 abstract · 3 Nov 2025

GLP-1 receptor agonists →

Associations

1

Cardiac allograft vasculopathy

upin humans1OR 1.138

1 study
  1. Cardiac allograft vasculopathy is associated with delta age in humans (median -1.0 vs. -11.0 years).

    Humansheart transplant recipients

    Discharge AI-ECG-Derived Age and Incidence of Cardiac Allograft Vasculopathy at 3 Years: A Pilot Study · Journal of cardiovascular development and disease · 20 Aug 2026

  2. Delta age predicts cardiac allograft vasculopathy in humans (adjusted OR 1.138, 95% CI 1.023-1.265).

    Humanspost-transplant discharge

    Discharge AI-ECG-Derived Age and Incidence of Cardiac Allograft Vasculopathy at 3 Years: A Pilot Study · Journal of cardiovascular development and disease · 20 Aug 2026

Cardiac allograft vasculopathy →

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