Cumulative Life's Essential 8 score

Cumulative Life's Essential 8 score is associated with increased arterial stiffness in humans (Highest versus lowest quartile: HR 0.15, 95% CI 0.12–0.18).

“Compared with quartile 1, the hazard ratios (95% confidence intervals) of quartile 2-4 were 0.69 (0.59-0.80), 0.41 (0.35-0.49), and 0.15 (0.12-0.18), respectively.”

HumansPatients with type 2 diabetes; highest versus lowest quartile of cumulative Life's Essential 8 scoreMedian follow-up of 9.76 yearsn = 2,685

Life's Essential 8 score and arterial stiffness in patients with type 2 diabetes

Archives of endocrinology and metabolism·15 Oct 2026