Cortical diffusion tensor metrics

Chronological age is associated with cortical diffusion tensor metrics in humans (U-shaped trajectories with minima at ~20-40 years).

“FA, MD, AD, and RD exhibited u-shaped trajectories reaching minimum values in adulthood (~20-40 years).”

Humanshealthy individuals; cross-sectional age comparisoncerebral cortexn = 190

High resolution diffusion tensor imaging of the human cortex reveals non-linear trajectories over the healthy lifespan

Imaging neuroscience (Cambridge, Mass.)·20 Aug 2025