Copper-to-zinc ratio

3 papers5 findings

Associations

Mortality

upin humans2

2 studies

Copper-to-zinc ratio predicts mortality in humans (aHR 1.50, 95% CI 1.06-2.13, p = 0.021).
“mortality (aHR 1.50, 95 % CI 1.06-2.13, p = 0.021)”
Humans5 years
Copper-to-zinc ratio predicts incident sarcopenia and adverse health outcomes: Results from I-Lan Longitudinal Aging Study
Experimental gerontology1 Dec 2025
Copper-to-zinc ratio predicts mortality in humans (AUC 0.755).
“The optimal cut-off value for predicting mortality was 1.67, with an area under the curve (AUC) of 0.755.”
Humansn = 280
The association between serum copper-to‑zinc ratio and mortality among older patients in the emergency department: A prospective cohort study in Taiwan
Experimental gerontology10 Nov 2025
Copper-to-zinc ratio raises the risk of mortality in humans (aHR 1.540 (95% CI 1.291-1.838)).
“In the multivariable Cox proportional hazards model, a high Cu/Zn ratio remained independently associated with increased 3-month mortality (adjusted hazard ratio = 1.540; 95 % CI: 1.291-1.838).”
Humansn = 280
The association between serum copper-to‑zinc ratio and mortality among older patients in the emergency department: A prospective cohort study in Taiwan
Experimental gerontology10 Nov 2025

Hospitalization

upin humans1

1 study

Copper-to-zinc ratio predicts hospitalization in humans (aHR 1.23, 95% CI 1.02-1.49, p = 0.030).
“hospitalization (aHR 1.23, 95 % CI 1.02-1.49, p = 0.030)”
Humans5 years
Copper-to-zinc ratio predicts incident sarcopenia and adverse health outcomes: Results from I-Lan Longitudinal Aging Study
Experimental gerontology1 Dec 2025

Sarcopenia

upin humans1

1 study

Copper-to-zinc ratio predicts sarcopenia in humans (aOR 1.39, 95% CI 1.13-1.73, p < 0.001).
“Each standard deviation increase in the Cu/Zn ratio was associated with higher risks of adverse outcomes (aHR 1.18, 95 % CI 1.04-1.33, p = 0.008), hospitalization (aHR 1.23, 95 % CI 1.02-1.49, p = 0.030), mortality (aHR 1.50, 95 % CI 1.06-2.13, p = 0.021), and incident sarcopenia (aOR 1.39, 95 % CI 1.13-1.73, p < 0.001).”
Humans3 years
Copper-to-zinc ratio predicts incident sarcopenia and adverse health outcomes: Results from I-Lan Longitudinal Aging Study
Experimental gerontology1 Dec 2025