Journal of Neurology, Neurosurgery, and Psychiatry
Brain scan patterns mark early changes in inherited dementia
In a cross-sectional study of 892 people, combined brain measurements helped distinguish mutation carriers with early symptoms from relatives without those mutations.In a cross-sectional study of 892 people, combined brain measurements helped distinguish mutation carriers with early symptoms from relatives without those mutations.
Cross-sectional · 892 peopleFrontotemporal dementia
Who was studied892 frontotemporal dementia mutation carriers and relatives
What changedGrey matter volume and cortical thickness were lower across brain regions in dementia mutation carriers than in mutation-negative relatives
The catchCorrelations with follow-up scores had reduced sample sizes of n=11, n=12, and n=8