Cognition-activation coupling

Age is associated with cognition-activation coupling in humans.

“Posterior midline regions shifted from positive to weaker or negative coupling with age, whereas left rostral Area 6 and IFJp showed the inverse pattern”

Humansregion-dependent changes in coupling strength and signposterior midline regions, left rostral Area 6 and IFJp0–12 years

Nonlinear Lifespan Trajectories of Memory and Fluid Reasoning: A Longitudinal GAMM Study

Research square·11 Dec 2025Preprint