cfDNA epigenetic clock

cfDNA epigenetic clock predicts chronological age in humans (125 CpGs).

“Besides, a cfDNA epigenetic clock comprising 125 CpGs is developed, demonstrating relatively high accuracy in predicting chronological age.”

Humansplasma cell-free DNAn = 98

Whole-genome profiling of age- and sex-associated DNA methylation signatures in human plasma cell-free DNA

Communications medicine·28 Nov 2025