BSAP/CTX ratio

1. Cholecalciferol increases BSAP/CTX ratio in humans (2.4 ± 0.6 vs 1.8 ± 0.5).

   “The liposomal form showed the highest ratio (2.4 ± 0.6 versus 1.8 ± 0.5 placebo; p = 0.001); hence, BSAP/CTX ratios were significantly better in all the active treatment groups.”

   Human trialT-scores -1.5 to -2.5liposomal800 IU/day + 1000 mg calcium24 monthsfemalesn = 153

   Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations

   European journal of clinical nutrition·7 Aug 2026

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