1 paper2 findings
Trabecular volumetric bone mineral density
downin humans1
Bone marrow fat is associated with trabecular volumetric bone mineral density in humans (-10.5% difference for each 1 SD increase in BMF, P < 0.01).
“BMF was associated with lower trabecular volumetric BMD (vBMD) at the spine (-10.5% difference for each 1 SD increase in BMF, P < 0.01)”
Humansspinefemalesn = 257
The Journal of clinical endocrinology and metabolism3 Apr 2013
Vertebral fracture
upin humans1
Bone marrow fat is associated with vertebral fracture in humans (57.3% vs 52.8%, P = 0.02).
“In separate models by sex, the difference was statistically significant only in men (57.3% vs 52.8%, P = 0.02).”
Humansadjusted for BMDvertebramalesn = 257
The Journal of clinical endocrinology and metabolism3 Apr 2013
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$1.4mVeterans Affairs
Bone marrow fat and skeletal health in type 2 diabetes
Veterans AffairsVeterans Affairs Med Ctr San Francisco2020–2025
National Institute of Arthritis and Musculoskeletal and Skin DiseasesHarvard Medical SchoolUS$550.9k2020–2026
Effects of DHEA and exercise on bone marrow fat in postmenopausal women
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUniversity of Colorado, DenverUS$303.6k2021–2026
In 81,318 UK Biobank adults, vertebral bone marrow fat rose 2.95% to 3.83% per decade across spinal regions, with higher levels in females.In 81,318 UK Biobank adults, vertebral bone marrow fat rose 2.95% to 3.83% per decade across spinal regions, with higher levels in females.