AHA Scientific Sessions 2026 Abstract
Clinical obesity genetic scores better predict cardiovascular risk
Clinical obesity genetic scores placed 34.6% of UK Biobank participants in different inherited obesity risk groups than genetic scores for body mass index.Clinical obesity genetic scores placed 34.6% of UK Biobank participants in different inherited obesity risk groups than genetic scores for body mass index.
Cohort studyClinical obesity
Who was studiedUK Biobank participants
What changedClinical obesity polygenic scores reclassified 34.6% of individuals, improving risk discrimination for myocardial infarction, heart failure, and stroke
The catchThe analysis did not measure whether score-guided care prevented cardiovascular events