Basal ganglia venous perivascular space burden

1. Basal ganglia venous perivascular space burden is associated with telephone Montreal Cognitive Assessment score in humans (β=-0.16).

   “only BG-vPVS burden independently correlated with lower scores after adjusting for age and education (β=-0.16, p=0.041).”

   HumansAdjusted for age and educationbasal ganglian = 60

   Deep Venous Perivascular Space Dysfunction Reflects Glymphatic Aging and Predicts Cognitive Vulnerability: In Vivo Human Evidence

   Aging and disease·May 15, 2026

1. Hypertension is associated with basal ganglia venous perivascular space burden in humans.

   “BG-vPVS burden correlated with age (r=0.275, p<0.001) and hypertension.”

   Humansbasal ganglian = 91

   Deep Venous Perivascular Space Dysfunction Reflects Glymphatic Aging and Predicts Cognitive Vulnerability: In Vivo Human Evidence

   Aging and disease·May 15, 2026

More on Hypertension

1. Age is associated with basal ganglia venous perivascular space burden in humans (r=0.275).

   “BG-vPVS burden correlated with age (r=0.275, p<0.001) and hypertension.”

   Humansbasal ganglian = 91

   Deep Venous Perivascular Space Dysfunction Reflects Glymphatic Aging and Predicts Cognitive Vulnerability: In Vivo Human Evidence

   Aging and disease·May 15, 2026