ATF5 expression

1. Sevoflurane increases ATF5 expression.

   “Sevoflurane preconditioning markedly increases ATF5 expression and its downstream target GDF15, a key regulator of mitochondrial homeostasis, in the cerebral cortex.”

   Animalssevoflurane preconditioning; species not statedcerebral cortex

   ATF5-Dependent GDF15 Expression Mediates Anesthesia-Induced Neuroprotection Against Stroke

   Advanced science (Weinheim, Baden-Wurttemberg, Germany)·26 Nov 2025

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