Aptamer staining
2 papers3 findings
- Animals2
Interventions
1Removal of P16 expressing cells
downin mice1
1 study
Removal of P16 expressing cells
downin mice1
Removal of P16 expressing cells decrease aptamer staining in mice.
“demonstrate decreased aptamer staining when p16 expressing cells are removed in a transgenic INK-ATTAC mouse model”
Animalsin a transgenic INK-ATTAC mouse model
An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents
bioRxiv : the preprint server for biologyMar 19, 2025Preprint
Upstream
2Removal of P16-EXPRESSING cells
downin animals1
1 study
Removal of P16-EXPRESSING cells
downin animals1
removal of p16-expressing cells decrease aptamer staining.
“demonstrate decreased aptamer staining when p16 expressing cells are removed in a transgenic INK-ATTAC mouse model”
Animalstransgenic INK-ATTAC mouse model
An Unbiased Cell-Culture Selection Yields DNA Aptamers as Novel Senescent Cell-Specific Reagents
Aging cellSep 19, 2025
Natural aging
upin mice1
1 study
Natural aging
upin mice1
Natural aging increases aptamer staining in mice.
“show increased aptamer staining in naturally aged mouse tissues”
Animalsnaturally agedmouse tissues
An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents
bioRxiv : the preprint server for biologyMar 19, 2025Preprint