Anti-SARS-CoV-2 spike RBD IgG

1. Nonsteroidal anti-inflammatory drugs decrease anti-SARS-CoV-2 spike RBD IgG in humans (aOR = 0.16, 95 %CI; 0.03-0.88).

   “regular nonsteroidal anti-inflammatory drugs [NSAIDs] usage (aOR = 0.16, 95 %CI; 0.03-0.88)”

   Humansmultivariate analysis after second doseserum

   Antibody responses after BNT162b2 vaccination in Japanese geriatric intermediate care facilities

   Vaccine: X·Nov 22, 2023

More on Nonsteroidal anti-inflammatory drugs

1. Steroids decrease anti-SARS-CoV-2 spike RBD IgG in humans (aOR = 0.09, 95 %CI; 0.01-0.60).

   “steroid usage (aOR = 0.09, 95 %CI; 0.01-0.60)”

   Humansmultivariate analysis after second doseserum

   Antibody responses after BNT162b2 vaccination in Japanese geriatric intermediate care facilities

   Vaccine: X·Nov 22, 2023

More on Steroids

1. Older age decreases anti-SARS-CoV-2 spike RBD IgG in humans (2282 AU/mL vs. 8505 AU/mL, and 258 U/mL vs. 948 U/mL).

   “After the second dose, geometric mean titers [GMT] of anti-RBD with both the Abbott and Roche assay were significantly lower in residents than staff”

   Humansresidents vs. staff after second doseserum

   Antibody responses after BNT162b2 vaccination in Japanese geriatric intermediate care facilities

   Vaccine: X·Nov 22, 2023