Preprints.org
Age-linked RNA processing differs in human brain and body
The spread of age-linked effects at the same RNA joining sites was 2.0–2.8 times as wide in brain as in body tissues from the same donors.The spread of age-linked effects at the same RNA joining sites was 2.0–2.8 times as wide in brain as in body tissues from the same donors.
Preprint: cross-sectional studyMechanisms
Who was studiedHuman tissue donors, against body tissues from the same donors
What changedAge-linked RNA splicing effects varied 2.0–2.8 times as widely in brain as in body tissues from the same donors
The catchBody-tissue age associations weakened substantially after accounting for ventilator use around death