AIVA
Biomarker1 paper4 findings
In a human study, higher AIVA is associated with poorer global cognition, brain infarcts, depressive symptoms and extensive white matter hyperintensities in multivariable models.
- Humans1
Associations
4Depressive symptoms
upin humans1OR 1.24
1 study
Depressive symptoms
upin humans1OR 1.24
AIVA is associated with depressive symptoms in humans (OR 1.24, 95% CI 1.08-1.41).
Humansin multivariable modelsn = 3,001
Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular Age · Arteriosclerosis, thrombosis, and vascular biology · 24 Sep 2026
Global cognition
downin humans1
1 study
Global cognition
downin humans1
AIVA is associated with global cognition in humans (β -0.07, 95% CI -0.12 to -0.03).
Humansin multivariable modelsn = 3,001
Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular Age · Arteriosclerosis, thrombosis, and vascular biology · 24 Sep 2026
Brain infarcts
upin humans1OR 1.44
1 study
Brain infarcts
upin humans1OR 1.44
AIVA is associated with brain infarcts in humans (OR 1.44, 95% CI 1.02-2.04).
Humansin multivariable modelsn = 2,313
Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular Age · Arteriosclerosis, thrombosis, and vascular biology · 24 Sep 2026
Extensive white matter hyperintensities
upin humans1OR 1.22
1 study
Extensive white matter hyperintensities
upin humans1OR 1.22
AIVA is associated with extensive white matter hyperintensities in humans (OR 1.22, 95% CI 1.02-1.47).
Humansin multivariable modelsn = 2,313
Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular Age · Arteriosclerosis, thrombosis, and vascular biology · 24 Sep 2026