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Aberrant DNA junctions

Biomarker

1 paper studies it1 more mentions it2 findings

  • Cells1

Upstream

1

Chronological aging

upin fission yeast cells1

1 study

  1. Chronological aging increases aberrant DNA junctions in fission yeast cells.

    “Aberrant DNA junctions that accumulated with age were associated with microhomology sequences and R-loops.”

    Cellschronological ageingnon-dividing cells

    R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

Associations

1

R-loops

upin fission yeast cells1

1 study

  1. R-loops are associated with aberrant DNA junctions in fission yeast cells.

    “Aberrant DNA junctions that accumulated with age were associated with microhomology sequences and R-loops.”

    Cellschronological ageingnon-dividing cells

    R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

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