4Kscore

1. 4Kscore predicts high-grade prostate cancer in humans (AUC 0.734 vs 0.595).

   “Predictions from the 4K model using adjusted markers improved discrimination over adjusted total PSA alone (AUC 0.734 vs 0.595; p < 0.001).”

   Human trialin men on finasteride biopsied for causemalesn = 459

   Estimating the Effect of Finasteride on Kallikrein Marker Levels in Blood and the Use of Converted Markers in the Four-Kallikrein Model

   European urology focus·Mar 20, 2026

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