17-gene transcriptomic proxy for mitoxyperilysis

1. 17-gene transcriptomic proxy for mitoxyperilysis has no effect on cellular senescence in silico.

   In siliconone of seven panel-disjoint patient-level tests met validation criteria

   Construct validity and evidence boundaries of a 17-gene transcriptomic proxy for mitoxyperilysis in colorectal aging and cancer Analysis

   Research Square·15 Sep 2026Preprint

More on Cellular senescence

1. 17-gene transcriptomic proxy for mitoxyperilysis is associated with senescence algorithms in silico (random-effects rho 0.339, 95% CI 0.172–0.486).

   In silicobulk CRC meta-analysis across cohortscolorectal cancer

   Construct validity and evidence boundaries of a 17-gene transcriptomic proxy for mitoxyperilysis in colorectal aging and cancer Analysis

   Research Square·15 Sep 2026Preprint

More on Senescence algorithms

1. 17-gene transcriptomic proxy for mitoxyperilysis is associated with chronological age in silico (Spearman rho 0.125 to 0.052).

   In silicounadjusted, then adjustedcolon

   Construct validity and evidence boundaries of a 17-gene transcriptomic proxy for mitoxyperilysis in colorectal aging and cancer Analysis

   Research Square·15 Sep 2026Preprint