11-protein plasma proteomic signature

Biomarker1 paper2 findings

  • Humans1

Effects

1

Harrell's C-index

upin humans1

1 study
  1. 11-protein plasma proteomic signature increases harrell's C-index in humans (from 0.798 to 0.862).

    Humansmedian follow-up 15.73 yearsn = 36,696

    An 11-protein blood score tracks incident dementia risk · Geriatrics & gerontology international · 1 Oct 2026

Associations

1

Dementia

upin humans1HR 2.645

1 study
  1. 11-protein plasma proteomic signature raises the risk of dementia in humans (HR 2.645, 95% CI 2.459-2.845).

    Humansmedian follow-up 15.73 yearsn = 36,696

    An 11-protein blood score tracks incident dementia risk · Geriatrics & gerontology international · 1 Oct 2026

Dementia →

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11
Geriatrics & Gerontology InternationalHumans

An 11-protein blood score tracks incident dementia risk

In over 36,000 UK Biobank participants, the signature raised Harrell's C-index from 0.798 to 0.862, carrying a hazard ratio of 2.645 per standard…In over 36,000 UK Biobank participants, the signature raised Harrell's C-index from 0.798 to 0.862, carrying a hazard ratio of 2.645 per standard deviation increase.