metformin

AssetSmall moleculeAlso Metformin DR, Glucovance, Metformin XR, Metformin Hydrochloride

Activates AMPK and reduces hepatic gluconeogenesis

Stage
Approved
Modality
Small molecule
Target
Mitochondrial biogenesis (PGC-1α)
Indications
22
Trials
1,347
Developers
12

Indications

22

19 more

  • Targets and what it contains6
  • Owner and partners12
  • Trials1,347
  • Evidence for its targets7
  • Competitors12
  • Aging relevance4
  • Signals15

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Updated 7 Oct 2026 · 43 sources

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