No phaseNot yet recruitingAge-related condition
Undenatured Type II Collagen for Knee Osteoarthritis Pain (FLEXICOL)
Randomized Clinical Trial to Analyze the Efficacy and Safety of Undenatured Type II Collagen Product on Joint Pain in Patients Diagnosed With Osteoarthritis
- Sponsor
- Universidad Católica San Antonio de Murcia (Academic or other)
- Enrolment
- 120 planned
- Conditions
- Osteoarthritis, Knee
- Interventions
- Placebo; Nuvicol II; Nuvicol SII
- Ages
- adults, older adults
- Registry
- NCT07870967
Full record on ClinicalTrials.gov
From the registry
This randomized, controlled, double-blind, three-arm parallel clinical trial will evaluate the efficacy and safety of undenatured type II collagen products on joint pain in adults diagnosed with knee osteoarthritis. Participants will be randomized to Nuvicol II, Nuvicol SII, or placebo and will consume one capsule daily for 4 months. Pain, quality of life, knee muscle function, concomitant analgesic medication use, cartilage degradation biomarkers, safety laboratory variables, and adverse events will be assessed during follow-up.
Primary outcomes
- Change in joint pain intensity measured by visual analog scale
History
Primary completion expected
Expected to start
Last registry update
Registered