Phase 2Recruiting
Alleviating Suicidality by Combining Psychotherapy and IM Ketamine for Rapid Treatment in the Emergency Department (ASPIRED)
ASPIRED: Alleviating Suicidality by Combining Psychotherapy and IM Ketamine for Rapid Treatment in the Emergency Department - A Randomized Clinical Trial.
- Sponsor
- The University of Texas Health Science Center at San Antonio (Academic or other)
- Enrolment
- 200 planned
- Conditions
- Suicidal Ideation
- Interventions
- Ketamine Injectable Solution; Placebo Injection; Crisis Response Plan; Safety Planning
- Ages
- adults, older adults
- Registry
- NCT07868913
Full record on ClinicalTrials.gov
From the registry
Participants are asked to take part in this research study after coming to the Emergency Department with thoughts or behaviors of seriously hurting themselves. There are very few resources to treat acute suicidal thoughts or behaviors in an emergency department. The purpose of this study is to evaluate the effectiveness of combining an intramuscular (IM) injection of ketamine and Crisis Response Planning (CRP), a single, 45-60 minute psychological intervention with a therapist, to quickly reduce suicidal thoughts in patients treated in an emergency department (ED) prior to being admitted to the hospital.
Primary outcomes
- Depressive Symptoms Index - Suicidality Subscale (DSI-SS)
History
Primary completion expected
Last registry update
Registered
Started