Phase 4Completed

Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars

A Split Face Comparative Study Between Fractional Carbon Dioxide Laser And Exosomes Versus Fractional Carbon Dioxide Laser And Skin Booster In The Treatment Of Post-Acne Scars

Sponsor
October 6 University (Academic or other)
Enrolment
30 enrolled
Conditions
Atrophic Acne Scar
Interventions
Fractional co2 laser; Exosomes; Hyaluronic Acid skin booster
Ages
adults, older adults
Registry
NCT07868445

Full record on ClinicalTrials.gov

From the registry

* Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited. * Adding topical exosomes via laser-assisted drug delivery may enhance scar remodeling and skin elasticity compared with HA, whereas HA provides superior hydration, supporting individualized treatment selection based on therapeutic goals. These findings are preliminary and require confirmation in larger studies.

Primary outcomes

  • Change in Post-Acne Atrophic Scar Severity Score

History

  1. Registered

  2. Primary completion

  3. Started