Phase 2/3Recruiting
Combination of Rituximab and Cyclosporine in the Treatment of Primary Membranous Nephropathy
Efficacy and Safety of Rituximab Combined With Cyclosporine for Primary Membranous Nephropathy
- Sponsor
- Peking University First Hospital (Academic or other)
- Enrolment
- 90 planned
- Conditions
- Membranous Nephropathy
- Interventions
- Rituximab combined with cyclosporine; rituximab
- Ages
- adults, older adults
- Registry
- NCT07861204
From the registry
High-grade proteinuria is one of the key determinants of adverse renal prognosis in patients with primary membranous nephropathy (PMN).The main purpose of this study is to determine whether Rituximab combined with Cyclosporine is superior to Rituximab monotherapy in inducing remission of proteinuria in patients with PMN.
Primary outcomes
- Remission Status