Phase 4Not yet recruiting

Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty

Low-Volume PENG Block With Dexamethasone Versus Standard-Volume PENG Block for Postoperative Analgesia and Quadriceps Function After Total Hip Arthroplasty

Sponsor
Ain Shams University (Academic or other)
Enrolment
60 planned
Conditions
Pain, Postoperative; Muscle Weakness; Arthroplasty, Replacement, Hip
Interventions
Pericapsular nerve group (PENG) block; Bupivacaine; Dexamethasone
Ages
adults, older adults
Registry
NCT07855341

From the registry

The goal of this clinical trial is to compare two regimens of the pericapsular nerve group (PENG) block, an ultrasound-guided injection of local anaesthetic targeting the nerves supplying the front of the hip joint, for postoperative pain relief and quadriceps muscle function in patients undergoing primary unilateral total hip arthroplasty under spinal anaesthesia. The PENG block was originally proposed as a motor-sparing technique. However, the standard 20 mL volume can spread to the femoral nerve and cause quadriceps weakness. Reducing the injected volume may limit this spread and better preserve quadriceps strength, but smaller volumes risk shorter analgesic duration. Adding dexamethasone to a low-volume injection may compensate for the reduced volume. The main questions this trial aims to answer are: * Does a low-volume PENG block (10 mL bupivacaine 0.25%) with 4 mg dexamethasone differ from a standard-volume PENG block (20 mL bupivacaine 0.25%) in the time to first rescue analgesia? * Does it differ in the incidence and severity of quadriceps weakness on the operated side?…

Primary outcomes

  • Time to First Rescue Analgesia
Full record on ClinicalTrials.gov