No phaseCompleted

Vaginal Prasterone Versus Estriol in Women With Pelvic Floor Disorders

Short-Term Vaginal Estriol Versus Prasterone in Women With Pelvic Floor Disorders: A Prospective Non-Randomized Comparative Study of Symptoms and Quality of Life"

Sponsor
Poznan University of Medical Sciences (Academic or other)
Enrolment
74 enrolled
Conditions
Pelvic Organ Prolapse (POP); Stress Urinary Incontinence (SUI)
Interventions
Prasterone (DHEA); Estriol
Ages
adults, older adults
Registry
NCT07854873

From the registry

This prospective, non-randomized comparative study evaluated the effects of short-term vaginal treatment with prasterone or estriol in women with pelvic floor disorders who were awaiting urogynecological surgery. A total of 74 women were included, with 37 participants receiving vaginal prasterone and 37 receiving vaginal estriol. Treatment was administered before surgery for approximately 8 weeks. The study assessed changes in pelvic floor symptoms and quality of life using the WHOQOL-BREF questionnaire and symptom severity scales. The aim was to compare the effects of the two vaginal treatments on symptoms and quality of life before urogynecological surgery.

Primary outcomes

  • Change in Quality of Life Measured by WHOQOL-BREF
Full record on ClinicalTrials.gov