Phase 4Enrolling by invitation
Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity
Optimizing Multimodal Pain Regimens: Evaluating the Analgesic Effect of Pill Quantity and Gabapentin in Reducing Opioid Dependency
- Sponsor
- AdventHealth (Academic or other)
- Enrolment
- 300 planned
- Conditions
- Opioid Abuse (Disorder); Opioid Analgesia; Opioid Analgesic Adverse Reaction; Opioid Consumption
- Interventions
- Naproxen; Acetaminophen; oxycodone; Gabapentin
- Ages
- adults, older adults
- Registry
- NCT07750639
Full record on ClinicalTrials.gov
From the registry
The goal of this clinical trial is to evaluate strategies for optimizing postoperative multimodal pain regimens and reducing opioid dependency in patients undergoing upper extremity surgery. The main questions it aims to answer are: * Does increasing the total physical quantity of non-opioid pills (Naproxen and Acetaminophen) prescribed in smaller individual doses alter a patient's self-reported postoperative pain scores, even when the total daily milligram dosage remains identical? * Does combining the non-opioid medication gabapentin with a significantly lower initial quantity of prescribed opioid pills (oxycodone) provide comparable pain relief and reduce the rate of subsequent medication refill requests? Researchers will compare three groups of participants receiving distinct standard-of-care pain management regimens to see how pill volume variations and gabapentin integration affect recovery. Participants will: * Be randomized into one of three standard postoperative pain medication groups varying in non-opioid pill counts or featuring a shortened opioid course combined…
Primary outcomes
- Number of Participants Requesting an Additional Postoperative Pain Medication Refill
History
Study completion expected
Primary completion expected
Last registry update
Registered
Started