Taurine Supplementation in Adolescents With Post-COVID Condition (TaurineLCPeds)

The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to experience persistent and debilitating symptoms long after the initial SARS-CoV-2 infection. This condition, known as Long COVID (LC) or sometimes referred to as Post-COVID Condition (PCC) or post-acute sequelae of COVID-19 (PASC), has emerged as a complex multisystemic condition and challenging public health issue. Contrary to initial perceptions, pediatric Long COVID is a significant health concern, with studies suggesting its prevalence ranges from 10% to 25% following infection. Research in the pediatric population has largely been limited to observational studies based on self-reported symptoms or large electronic healthcare datasets. The long-term outcomes and predictors of LC in children remain poorly described, highlighting an urgent need for further mechanistic research to characterize this complex condition. While acute COVID-19 symptoms are often…

• Mean Change in Plasma Taurine Levels from Baseline to Three Months

1. Study completion expected

   31 Dec 2028

2. Primary completion expected

   31 Mar 2028

3. Expected to start

   30 Dec 2026

4. Last registry update

   16 Oct 2026

5. Registered

   2 Jul 2026