No phaseCompleted
NMES Plus Hypocaloric Diet: Body Composition, Cardiometabolic Markers, Irisin and Betatrophin in Women With Obesity
Effects of Neuromuscular Electrical Stimulation Combined With a Hypocaloric Diet on Body Composition, Cardiometabolic Markers, Irisin and Betatrophin in Women With Obesity: A Randomized Controlled Trial
- Sponsor
- Firat University (Academic or other)
- Enrolment
- 44 enrolled
- Conditions
- Obesity
- Interventions
- Hypocaloric Diet; Neuromuscular Electrical Stimulation (NMES)
- Ages
- adults, older adults
- Registry
- NCT07675382
Full record on ClinicalTrials.gov
From the registry
This randomized controlled trial evaluated whether adding localized neuromuscular electrical stimulation (NMES) to an individualized hypocaloric diet changes serum irisin and betatrophin (ANGPTL8) concentrations, body composition and cardiometabolic markers in women with obesity, compared with the diet alone. Forty-four women aged 18-65 years with a body mass index (BMI) of 30 kg/m2 or more were randomly assigned (1:1) to a diet-only group or a diet plus NMES group. NMES was applied to the abdominal and gluteal muscles twice weekly for six weeks (12 sessions of 20-25 minutes). The primary outcomes were the changes in serum irisin and betatrophin; the secondary outcomes were the changes in body weight, BMI, body fat percentage, fat mass, skeletal muscle mass and cardiometabolic markers, assessed at baseline and at the end of week 6.
Primary outcomes
- Change in Serum Irisin Concentration
- Change in Serum Betatrophin (ANGPTL8) Concentration
History
Last registry update
Registered
Primary completion
Started