No phaseCompleted
Effect of a Probiotic Formulation in Adults With Lactose Intolerance and Methanogenic Intestinal Overgrowth (LAC L-134/33)
Effect of a Probiotic Formulation (Lacticaseibacillus Rhamnosus - Limosilactobacillus Fermentum) on Gastrointestinal Symptoms in Adults With Lactose Intolerance and Methanogenic Intestinal Overgrowth
- Sponsor
- Universidad de Concepcion (Academic or other)
- Enrolment
- 22 enrolled
- Conditions
- Lactose Intolerance
- Interventions
- Probiotic formulation; Maltodextrin (Placebo)
- Ages
- adults, older adults
- Registry
- NCT07652827
Full record on ClinicalTrials.gov
From the registry
Introduction: Lactose intolerance (LI) is characterized by specific gastrointestinal symptoms following the consumption of dairy products and lactose-containing foods, symptoms that may also be experienced by individuals with intestinal methanogenic overgrowth (IMO). However, such clinical manifestations may be modulated by the use of probiotics; the aim of this study was to analyze the preliminary efficacy of a probiotic formulation on gastrointestinal symptoms in adults with LI and IMO. Materials and Methods: A randomized, double-blind, placebo-controlled pilot study was conducted with 22 adults who tested positive on a hydrogen breath test (HBT); they were assigned to intervention or placebo groups based on their diagnosis. Accordingly, they completed a Questionnaire on symptoms of Lactose Intolerance (QSLT) and underwent successive nutritional assessments.
Primary outcomes
- Hydrogen breath test (HBT)
History
Last registry update
Registered
Study completion
Primary completion
Started