Phase 4Completed
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome (SGLT-2/PCOS)
- Sponsor
- Beni-Suef University (Academic or other)
- Enrolment
- 500 enrolled
- Conditions
- Induction of Ovulation; PCO - Polycystic Ovaries
- Interventions
- Metformin 1000 mg Oral Tablet; Dapagliflozin 10 MG Oral Tablet [Farxiga]; Combined Dapagliflozin-Metformin 5/1000mg; Letrozole 2.5Mg Tablet
- Ages
- adults
- Registry
- NCT07589075
From the registry
The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing specifically on rates of ovulation and pregnancy.
Primary outcomes
- Ovulation rate
- Pregnancy rate