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Phase 2RecruitingAge-related condition

Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis

A Phase IIb, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis

Sponsor
Enlivex Therapeutics Ltd. (Industry)
Enrolment
182 planned
Conditions
Primary Knee Osteoarthritis
Interventions
Allocetra; Placebo
Ages
adults, older adults
Registry
NCT07580716

Full record on ClinicalTrials.gov

From the registry

This is a multicenter, randomized, double-blind, placebo-controlled, Phase IIb study to evaluate intra-articular (IA) injections of Allocetra in participants with moderate-to-severe age related symptomatic primary knee osteoarthritis (OA).

Primary outcomes

  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain score at 3 months
  • Western Ontario and McMaster Universities Arthritis Index (WOMAC) Function score at 3 months
  • Primary Safety Endpoint

History

  1. Study completion expected

  2. Primary completion expected

  3. Last registry update

  4. Registered

  5. Started