No phaseRecruiting
Ultrasonic Debris Clearance to Promote Brain Resilience
Safety and Feasibility Trial of Ultrasonic Debris Clearance to Promote Brain Resilience
- Sponsor
- Stanford University (Academic or other)
- Enrolment
- 15 planned
- Conditions
- Alzheimer s Disease; MCI With Increased Risk for Alzheimer Disease
- Interventions
- Ultrasonic Debris Clearance; sham
- Ages
- adults, older adults
- Registry
- NCT07573982
From the registry
This pilot study will evaluate the safety, tolerability, and feasibility of Ultrasonic Debris Clearance (UDC), a noninvasive low-intensity focused ultrasound intervention, in amyloid-positive adults who are asymptomatic but at risk for Alzheimer's disease, or who have mild cognitive impairment or mild dementia. The study is designed to test whether repeated UDC sessions can be delivered safely and feasibly in this population, while also exploring efficacy via biomarkers and clinical measures.
Primary outcomes
- Number of Participants with Treatment-Related Adverse Events